Cutaneous infection caused by Aspergillus ustus, an emerging opportunisticfungus in immunosuppressed patients

We report a case of primary cutaneous infection by the emerging fungus Aspe rgillus ustus in an immunosuppressed patient after a domestic accident. The patient failed to respond to itraconazole and died before receiving a new treatment with amphotericin B. There have been eight other cases reported s ince 1973, and only two patients survived the infection. In vitro susceptib ility testing of seven antifungal drugs showed that terbinafine and the new azole derivative UR-9825 were the most active against this fungus.