Comparison of IsoCode STIX and FTA gene guard collection matrices as whole-blood storage and processing devices for diagnosis of malaria by PCR

Authors
Zhong, KJY Salas, CJ Shafer, R Gubanov, A Gasser, RA Magill, AJ Forney, JR Kain, KC
Citation
Kjy. Zhong et al., Comparison of IsoCode STIX and FTA gene guard collection matrices as whole-blood storage and processing devices for diagnosis of malaria by PCR, J CLIN MICR, 39(3), 2001, pp. 1195-1196
Citations number
11
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
39
Issue
3
Year of publication
2001
Pages
1195 - 1196
Database
ISI
SICI code
0095-1137(200103)39:3<1195:COISAF>2.0.ZU;2-A
Abstract
We compared two collection devices, IsoCode and FTA, with whole blood for t he diagnosis of malaria by PCR (n = 100). Using whole blood as the referenc e standard, both devices were sensitive for the detection of single-species malaria infections by PCR (greater than or equal to 96%). However, the det ection of mixed infections was suboptimal (IsoCode was 42% sensitive, and F TA was 63% sensitive).