Peritoneal dialysis in an infant with Type 1 diabetes and hyperosmolar coma

Hyperosmolar coma which is characterized by severe hyperglycemia in absence of chetosis is very rare in pediatric age with only 11 cases reported in t he literature. The outcome of the condition is usually poor with mental ret ardation being the most common event. Here a case of hyperosmolar coma is d escribed in a female of three months of age who was treated with peritoneal dialysis 11 hours after admittance to hospital. This female patient has be en receiving insulin from three months of age and today at the age of 10 ye ars she leads a normal life despite being on insulin therapy. A very low le vel of C-peptide (<0.3 ng/ml) clearly confirms she is affected by Type 1 di abetes. To our knowledge this is the first case report of hyperosmolar coma in a neonate with Type 1. diabetes who survived this condition without lat e neurological consequences. (C)2001. Editrice Kurtis.