Brucellosis is a common zoonosis in many parts of the world. Human brucello
sis is a multisystemic disease with a wide range of clinical symptoms. Bill
iary involvement in the Form of acute cholecystitis is a very rare manifest
ation of brucellosis. Here we report the case of a 34-year-old male with ac
ute cholecystitis caused by Brucella melitensis and review seven other case
s. We conclude that brucella may have a focal effect on the gallbladder, in
the form of acute chelocystitis. (C) 2001 The British Infection Society.