K. Tsunoda et al., Autologous transplantation of fascia into the vocal fold: Long-term results of a new phonosurgical technique for glottal incompetence, LARYNGOSCOP, 111(3), 2001, pp. 453-457
Objectives: To study the long-term results of autologous transplantation of
fascia into the vocal fold, and to evaluate our use of autologous transpla
ntation instead of bovine collagen injection in cases of glottal incompeten
ce. Study Design: Retrospective study of the patients who have undergone au
tologous fascia transplantation using our new technique. Methods: Follow-up
studies were performed for at least 1 year (up to 3 y) on 9 autologous fas
cia transplant patients (6 cases with type 1 procedures and 3 cases with ty
pe 2 procedures), Clinical observations, including laryngeal stroboscopy, a
nd measurement of maximum phonation time (MPT) were carried out. Results: D
uring 3 months after autologous fascia transplantation, MPT gradually incre
ased and stroboscopy showed improved glottal closure. These improvements co
ntinued beyond 1 year in all cases of type 1 surgery and 2 of 3 cases of ty
pe 2 surgery. Conclusions: Autologous transplantation of fascia into the vo
cal folds as a phonosurgical treatment for glottal incompetence yields exce
llent long-term results. Temporal fascia appears to be a highly suitable ti
ssue for transplantation in Reinke's space. However, the fascia is less sui
table for transplantation in the muscle. We speculate that transplantation
of temporal fascia leads to regeneration of vocal fold tissue, perhaps usin
g a mechanism similar to stem cell transplantation in other organs.