Correlation analyses between the mobilities on paper electrophoresis of alkysubstituted phosphonium ions (RR ' P-3(+))

To make use for separation and qualitative analysis of phosphonium ions, pa per electrophoresis method was applied to the analysis of 40 kinds of phosp honium ions (RR3'P+) obtained from the reactions of trimethyl-, triethyl-, tributyl- and triphenylphosphine (R-3'P) with methyl-, ethyl-, propyl-, but yl-, benzyl-, acetylmethyl-, benzoylmethyl-, methoxycarbonylmethyl-, ethoxy carbonylmethyl- and cyanomethyl halides (RX). Good correlations were found between the average mobilities and the molecular structural parameters such as molecular weights, molecular volumes, and molecular surface areas. The slopes for the regression line between the average mobilities of each phosp honium ion and the structural parameters tend to increase with the increase of the pH of the buffer solution used. It was proved that this behavior se rve to differentiate and analyze the phosphonium ions according to the subs tituents on the phosphonium ions.