Retrocorneal membranes after penetrating keratoplasty (PKP) is a well known
complications, resulting from unintentional retention of the host Descemet
's membrane (DM), or donor DM detachment. We describe for the first time th
e formation of a retrocorneal inflammatory membrane that mimics donor DM de
tachment or retained recipient DM, and discuss the differential diagnosis o
f a retrocorneal membrane after PKP! Two patients who underwent PKP and sub
sequently developed a retrocorneal membrane are described. In both patients
' eyes a retrocorneal membrane was observed immediately following penetrati
ng keratoplasty. While the first patient's membrane persisted for 33 months
in the presence of a clear graft, the second patient's membrane disintegra
ted and dissolved within two weeks following treatment with topical steroid
s. The first case describes a patient with retained Descemet's membrane, wh
ile in the second case, it turned out that the retrocorneal membrane was ac
tually an inflammatory membrane.