Aggressive angiomyxoma of the spermatic cord. Two unusual cases occurring in childhood

We report on two cases of aggressive angiomyxoma (AAM) of the spermatic cor d occurring in two 13-year-old children. Clinically, the tumor simulated a mass of the spermatic cord. Histologically, it represented a poorly circums cribed, benign myxoid tumor, with a sparse population of stromal cells immu noreactive for vimentin and, focally, for smooth muscle actin. No immunosta ining for desmin, S-100, p53, p21(waf-1), c-Erb-B2 and estrogen-progesteron e receptors was found. High proliferating cell nuclear antigen (PCNA) immun oexpression found in most of the tumor cells may explain the high risk of r ecurrence. AAM should be considered in the differential diagnosis of a sper matic cord mass occurring during infancy.