MEGLUMINE GADOTERATE - A NEW SAFE RADIOCONTRAST MEDIUM FOR ENDOSCOPICRETROGRADE CHOLANGIOPANCREATOGRAPHY

The radiocontrast substance meglumine gadoterate (MG) is used in magne tic resonance imaging. It is characterized by its low rate of adverse drug reactions. In an open study we tested whether MG is useful in end oscopic retrograde cholangiopancreatography. The patients received in sequence MG and ioxotalamate. MG, in contrast to ioxotalamate, failed to visualize the proximal pancreatic and peripheral intrahepatic ducts . Thus, MG is not useful in routine endoscopic retrograde cholangiopan creatography. However, in patients with a history of severe allergic r eactions to conventional contrast media, MG may be recommended when pa thological findings of the extrahepatic bile duct or the area of the p ancreatic head are suspected.