Since Lapides reintroduced clean intermittent catheterization (CIC) in 1972
, this procedure has been used routinely in individualized programmes for b
ladder evacuation in various bladder disorders. It has been suggested that
in clinical practice hydrophilic catheters are preferable to non-coated cat
heters, In reviewing the literature on CIC, many of the reports were found
to rely on data from non-randomized retrospective studies. In some recent p
rospective studies, involving a limited number of patients, hydrophilic and
non-coated catheters have been evaluated and compared, especially with reg
ard to bacteriuria and urethral irritation. The available data indicate tha
t using hydrophilic catheters for CIC may induce lower rates of bacteriuria
and long-term urethral complications such as urethral strictures. However,
to reach a reliable conclusion about the supposed advantage of the hydroph
ilic catheters, there is a need for a prospective, randomized long-tron mul
ticentre study. It is important in such a study to define patient character
istics including age, gender, diagnosis of bladder dysfunction, reason for
CIC, physical and mental handicap, manual dexterity and previous treatments
. Effect parameters should include number of catheterizations, urinary trac
t infection, early and long-term urethral complications, patient satisfacti
on, preferences and dropout rates. It is obligatory to include factors such
as cost-benefit and cost-effectiveness.