A new assay system for phenacetin using biomimic bulk acoustic wave sensorwith a molecularly imprinted polymer coating

Citation
Yg. Tan et al., A new assay system for phenacetin using biomimic bulk acoustic wave sensorwith a molecularly imprinted polymer coating, SENS ACTU-B, 73(2-3), 2001, pp. 179-184
Citations number
24
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences","Instrumentation & Measurement
Journal title
SENSORS AND ACTUATORS B-CHEMICAL
ISSN journal
09254005 → ACNP
Volume
73
Issue
2-3
Year of publication
2001
Pages
179 - 184
Database
ISI
SICI code
0925-4005(20010310)73:2-3<179:ANASFP>2.0.ZU;2-2
Abstract
A new biomimic bulk acoustic wave (BAW) sensor with a molecularly imprinted polymer (MIP) coating has been designed and applied to the determination o f phenacetin in human serum and urine. The MIP was prepared using phenaceti n as the imprinted molecule and methacrylic acid as the functional monomer. The sensor showed high selectivity and sensitivity in aqueous system. A li near calibration response curve between 5.0 x 10(-8) M and 5.0 x 10(-4) M w as obtained and the detection limit was 5.0 x 10(-9) M. The coating of the sensor was stable and can be reused for many times. In the determination of real samples, satisfactory results were achieved. (C) 2001 Elsevier Scienc e B.V. All rights reserved.