Stereoselective double ring closing metathesis reactions in the synthesis of spirocyclic compounds

Authors
Wallace, DJ Bulger, PG Kennedy, DJ Ashwood, MS Cottrell, IF Dolling, UH
Citation
Dj. Wallace et al., Stereoselective double ring closing metathesis reactions in the synthesis of spirocyclic compounds, SYNLETT, (3), 2001, pp. 357-360
Citations number
27
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
3
Year of publication
2001
Pages
357 - 360
Database
ISI
SICI code
0936-5214(200103):3<357:SDRCMR>2.0.ZU;2-E
Abstract
The double ring closing metathesis reaction of alpha -hydroxyester derived tetraenes 4 proceed to give spirocyclic dihydropyrans in excellent yield an d with good selectivity. The first examples of diastereoselective double RC M reactions to give medium ring spirocycles are also reported.