Reaction of piperazine with trimethylacetic arylcarboxylic anhydride; A convenient method for preparing monoacylated piperazine derivatives

Authors
Lai, LL Wang, ES Luh, BJ
Citation
Ll. Lai et al., Reaction of piperazine with trimethylacetic arylcarboxylic anhydride; A convenient method for preparing monoacylated piperazine derivatives, SYNTHESIS-S, (3), 2001, pp. 361-363
Citations number
24
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
3
Year of publication
2001
Pages
361 - 363
Database
ISI
SICI code
0039-7881(200103):3<361:ROPWTA>2.0.ZU;2-X
Abstract
A series of monosubstituted piperazine derivatives were obtained by the rea ction of piperazine with trimethylacetic arylcarboxylic anhydrides in good yields, which were prepared in situ from arylcarboxylic acid with trimethyl acetyl chloride in the presence of triethylamine.