Use of PyBOP as a convenient activator for the synthesis of nitriles from primary amides

Authors
Bose, DS Narsaiah, AV
Citation
Ds. Bose et Av. Narsaiah, Use of PyBOP as a convenient activator for the synthesis of nitriles from primary amides, SYNTHESIS-S, (3), 2001, pp. 373-375
Citations number
31
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
3
Year of publication
2001
Pages
373 - 375
Database
ISI
SICI code
0039-7881(200103):3<373:UOPAAC>2.0.ZU;2-U
Abstract
Various types of primary carboxamides were reacted with benzotriazol-1-ylox ytris(pyrrolidino)phosphonium hexafluorophosphate (PyBOP) and N-ethyldiisop ropylamine to obtain the corresponding nitriles in high yields.