Synthesis of a sterically hindered diazirine with a satisfactory yield: Optically active 2-azicamphane

The optimized synthesis of 2-azicamphane (5), a sterically hindered 3,3-dia lkyldiazirine, has finally made this interesting chiral diazirine available in useful quantities. The specific reaction conditions are discussed with regard to further general applications for future syntheses of diazirines t hat, until now, could not be prepared.