Synthesis of an amphiphilic aldehyde using as a key step the condensation of a lipophilic glyoxylic acid amide derivative tris(hydroxymethyl)aminomethane

Authors
Bonnet, D Joly, P Gras-Masse, H Melnyk, O
Citation
D. Bonnet et al., Synthesis of an amphiphilic aldehyde using as a key step the condensation of a lipophilic glyoxylic acid amide derivative tris(hydroxymethyl)aminomethane, TETRAHEDR L, 42(10), 2001, pp. 1875-1877
Citations number
17
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
10
Year of publication
2001
Pages
1875 - 1877
Database
ISI
SICI code
0040-4039(20010304)42:10<1875:SOAAAU>2.0.ZU;2-7
Abstract
Spontaneous condensation of a glyoxylic acid amide derivative incorporating a palmitoyl group with tris(hydroxymethyl)aminomethane followed by Dess-Ma rtin oxidation led to an heterocyclic amphiphilic aldehyde, which was succe ssfully engaged in hydrazone formation in partial aqueous media. (C) 2001 P ublished by Elsevier Science Ltd.