M. Wang et al., Antitumour activity of transition metal complexes with the thiosemicarbazone derived from 3-acetylumbelliferone, TRANSIT MET, 26(3), 2001, pp. 307-310
Metal complexes of a new thiosemicarbazone derived from 3-acetylumbellifero
ne (HL) have been prepared and characterized. The complexes have the genera
l formula ML2 . nH(2)O where M-II = Co, Ni, Cu and Zn; n = 0 and 2. The lig
and and its complexes have been studied for their possible antitumour activ
ity against HL-60 human leukemia in vitro.