Two cases of vascular tumors of large vessels with intraluminal growth simu
lating venous thrombosis and arterial occlusive disease are reported. One w
as a borderline malignant epithelioid hemangioendothelioma of the femoral v
ein and the other a malignant epithelioid angiosarcoma of the carotid arter
y. Immunohistochemical studies permitted to classify the tumors. Treatment
consisted in surgical resection. No recurrence and no metastasis are noted
at 24 months. Uncertainty regarding biological behaviour of vascular tumors
and treatment persists.