In this paper we compare the sequence of the gene HSP150/PIR2, independentl
y determined by two different groups, with that present in the yeast databa
se as YJL159w, determined within the Yeast Sequencing Project. Although YJL
159w is believed to encode Hsp150/Pir2, there are important differences bet
ween the amino acid sequence coded by this ORF and that of HSP150/PIR2, To
find out if this divergence is due to strain polymorphism or to a possible
sequencing error, me have analysed the diverging zone of this ORF in three
strains and have found it entirely consistent with the sequence reported as
HSP150/PIR2, concluding that the divergence is probably due to a sequencin
g error in YJL159w. Copyright (C) 2001 John Wiley & Sons, Ltd.