New semisynthetic antimicrobial labdane-type diterpenoids derived from theresin "Ladano" of Cistus creticus

Authors
Kalpoutzakis, E Aligiannis, N Mitaku, S Chinou, I Harvala, C Skaltsounis, AL
Citation
E. Kalpoutzakis et al., New semisynthetic antimicrobial labdane-type diterpenoids derived from theresin "Ladano" of Cistus creticus, Z NATURFO C, 56(1-2), 2001, pp. 49-52
Citations number
11
Categorie Soggetti
Biochemistry & Biophysics
Journal title
ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
ISSN journal
09395075 → ACNP
Volume
56
Issue
1-2
Year of publication
2001
Pages
49 - 52
Database
ISI
SICI code
0939-5075(200101/02)56:1-2<49:NSALDD>2.0.ZU;2-5
Abstract
The antimicrobial activity of fifteen semisynthetic labdane-type diterpenes derived from the two major natural compounds 3 and 4 of the resin. "ladano " of Cistus creticus is reported. The chloroethyl carbamidic esters 15 and 20 showed the strongest antimicrobial activity against Gram (+), Gram (-) b acteria and pathogenic fungi.