Objective: To explore the biology of nicotine addiction and to investigate
the latest pharmacological treatments for nicotine dependence. Methods: Exp
lore the research literature for treating nicotine dependence. Results: Nic
otine is an additive drug and the most effective methods for treating depen
dence are nicotine replacement therapy (NRT) and bupropion SR. Conclusion:
The best available treatments for nicotine dependence are pharmacological a
djuncts; specifically, NRT and bupropion SR when combined with behavioral c
ounseling.