Objective: To demonstrate the use of logistic regression in health care res
earch. Method: Forward and backward stepwise logistic regression algorithms
were systematically applied to a real-world data set comprising 301 cancer
patients and a set of explanatory variables. Results: Four variables were
identified as effective predictors of pain reporting by cancer patients dur
ing chemotherapy: fatigue, depression, severity of colds or viral infection
s, and insomnia. The 4-predictor model was validated by (a) significance te
sts of regression coefficients at p<0.05, (b) significant improvement of th
is model over competing models, and (c) goodness of fit indices. Conclusion
s: Logistic regression is useful for health-related research in which outco
mes of interest are often categorical.