Many atypical forms of sarcoidosis have been described. mediastinum-lung in
volvement, observed in 90% of the cases, may cause atypical manifestations:
hemoptysis, chest pain, predominant pleural or proximal bronchial involvem
ent, Diffuse "unpolished glass" images or air cavities may be observed on t
he chest x-ray. A rigorous diagnostic work-up is necessary for these atypic
al forms. Pathological confirmation is mandatory: non-caseous tuberculoid g
ranuloma, A very wide range of extra-thoracic localizations have been descr
ibed with variable clinical manifestations. In cases with no mediastinum-lu
ng involvement, pathology data must be confronted with the notion of multip
le organ dissemination to reach diagnosis.