Average percentages of winter wheat plants with severe take-all were decrea
sed by up to half by azoxystrobin applied as foliar sprays in four field ex
periments. Decreased take-all in three of the experiments was associated wi
th increased grain yield but effects on other diseases may have contributed
to these responses. Standard fungicide sprays were ineffective. The effect
s differed, but not consistently, among different cultivars that were teste
d in three of the experiments. One, two or three sprays of azoxystrobin or
kresoxim-methyl, in autumn, spring or summer, were tested in the fourth exp
eriment. Unlike azoxystrobin, kresoxim-methyl had no consistent effects but
a smaller amount was applied. Two or three sprays of azoxystrobin were mor
e effective than a single spray but their timing was unimportant. Such cont
rol of a root disease by a foliar-applied fungicide is unusual but may help
to explain some of the unexpectedly large yield responses to azoxystrobin
that have been reported. This relatively broad-spectrum fungicide may have
the potential to contribute to the practical management of take-all but fur
ther research is needed to determine how best to exploit its effects consis
tently.