Xeroderma pigmentosum. report of 6 cases in Dakar

We report 6 cases of black Senegalese boys with xeroderma Pi,pigmentosum. T hey were between 2 and 16 year-old and presented features of hypersensitivi ty to UV (keratosis, lentigines, poikilodermia and photophobia). Our cases were remarkable by the early occurrence of squamous cell and basal cell car cinoma located in photoexposed sites causing the death of 5 of them. Xerode rma pigmentosum must be considered ns the first preneoplastic genodermatosi s.