The dynamic simulation of chromatographic separation of citric acid

This paper provides a suitable method for studying thermal swing chromatogr aphic kinetics and estimation of model parameters, considering the change o f bed porosity. As an experimental example, the separation of the citric ac id is discussed. The model parameters were measured on an analytical column . With these thermodynamic parameters it was attempted to simulate the sepa ration behaviour in larger columns using the equilibrium dispersive model, the result was very satisfactory.