Benign uterine leiomyoma with metastatic pulmonary nodales

Pulmonary nodules resected in 10 patients were histologically classified as benign metastatic leiomyoma of the uterus. Hysterectomy because of myoma h ad been performed between 0 and 24 years earlier (median 14.9 years). Betwe en 1 and 27 nodules were found in one or both lungs. Patients presenting wi th a single nodule had it resected with diagnostic intent and were followed up. Multiple nodules were resected if the loss of parenchyma was tolerable ; otherwise, one lesion was resected for diagnosis. In some cases antihormo nal therapy was performed postoperatively. The median duration of follow-up was 4.7 years. In this time, no local complication occurred, and no patien t died of this disease. Apparently, benign metastatic leiomyoma of the uter us biologically shows benign behaviour. New manifestation or progressing gr owth of non-resected lesions does occur, however. Consequently, regular fol low-up is required. Local complications indicate surgical intervention.