Increasing prevalence of diabetes mellitus and impaired glucose tolerance among 60-year-old Danes

Citation
T. Drivsholm et al., Increasing prevalence of diabetes mellitus and impaired glucose tolerance among 60-year-old Danes, DIABET MED, 18(2), 2001, pp. 126-132
Citations number
26
Categorie Soggetti
Endocrynology, Metabolism & Nutrition
Journal title
DIABETIC MEDICINE
ISSN journal
07423071 → ACNP
Volume
18
Issue
2
Year of publication
2001
Pages
126 - 132
Database
ISI
SICI code
0742-3071(200102)18:2<126:IPODMA>2.0.ZU;2-H
Abstract
Aims The age-specific prevalence of diabetes mellitus and impaired glucose tolerance (IGT) was estimated in 60-year-old individuals in 1996/97 and com pared to the prevalence in 1974/75. The study also examined whether or not the change in prevalence of diabetes and IGT could be explained by changes in body mass index (BMI) and physical activity. Methods Diabetes and IGT were diagnosed by a standardized oral glucose tole rance test (OGTT) in two Danish population-based, age-specific, birth cohor ts. Results The prevalence of diabetes in 1996/97 was 12.3% among 60-year-old m en and 6.8% among women, representing an increase in diabetes of 58% in men and 21% in women compared to 1974/75. The prevalence of IGT was 15.9% amon g men and 13.1% among women, representing increases of 109 and 16%, respect ively. A concurrent increase in BMI in the 22-year period between the two s tudies explained the increase found in the prevalence of diabetes and IGT. Conclusions A marked increase in the prevalence of diabetes and IGT among 6 0-year-old individuals over a 22-year period was observed - especially in m en. The increase was fully explained by a concurrent increase in BMI.