Silicon nitride (Si3N4) sensing gate pa-ion-selective field effect transist
ors (ISFETs) were treated by 2,54-GHz microwave O-2 plasma, the results sho
w the ISFET sensitivity has an advantage up to 24% increment after the plas
ma treatment. Electron spectroscopy for chemical analysis (ESCA) is used to
make sure that the plasma treatment is not just a native oxide cleaning pr
ocedure, The samples, which were immobilized with glutaraldehyde used as a
bifunctional reagent and 3-aminopropyltriethoxysilane used as an adhesion p
romoter were studied. The binding force between the glucose oxidase and glu
taraldehyde immobilized samples, and the element concentrations of nitrogen
in 3-aminopropyltriethoxysilane immobilized samples are higher which were
treated by plasma.