C. Kreutzer et al., PREOPERATIVE MANAGEMENT OF CONGESTIVE-HEART-FAILURE IN NEONATES - THECLOSED HOOD, International journal of cardiology, 60(2), 1997, pp. 139-142
In this study we report the results of the use of a closed hood with n
o external administration of CO2 to increase pulmonary vascular resist
ance by lowering the inspired fraction of oxygen (FiO(2)) and raising
the inspired fraction of carbon dioxide (FiCO(2)) in patients with con
genital heart disease and increased pulmonary blood flow. Between Dece
mber 1995 and May 1996, 9 neonates (F:5, M:4) were admitted. Each stud
y patient was assigned to clinical classes using a 1 to 4 classificati
on. Ages ranged between 2 and 30 days (mean 18), weight between 2.25 a
nd 3.65 kg (mean 2.89). A plastic hood, closed on the top with a plast
ic membrane and with the gas entrance open to room air was placed over
the head of the patients. Patients increase pCO(2) by rebreathing the
ir own expired CO2. After 24 h of the onset of the treatment the media
of points of congestive heart failure 1 to 4 classification decrease
from a mean of 4 to a mean of 2.28 +/- 0.44 (p = 0.001). A statistical
ly significant improvement in symptoms and lowering of pO(2) and pH wh
ile raising pCO(2) has been demonstrated in this study. (C) 1997 Elsev
ier Science Ireland Ltd.