Thallium(III) salts in heterocyclic synthesis: Synthesis of 3-aryl-9-methyl-1,2,4-triazolo[4,3-a]quinolines

Authors
Singh, OV Muthukrishnan, M Sundaravadivelu, M
Citation
Ov. Singh et al., Thallium(III) salts in heterocyclic synthesis: Synthesis of 3-aryl-9-methyl-1,2,4-triazolo[4,3-a]quinolines, I J CHEM B, 40(3), 2001, pp. 262-265
Citations number
19
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
ISSN journal
03764699 → ACNP
Volume
40
Issue
3
Year of publication
2001
Pages
262 - 265
Database
ISI
SICI code
0376-4699(200103)40:3<262:TSIHSS>2.0.ZU;2-2
Abstract
Oxidation of arenecarbaldehyde 4-methylquinolin-2-ylhydrazones 2a-h with th allium(III) acetate in acetic acid, thallium(III) acetate and thallium(III) nitrate in acetonitrile or methanol in the presence of perchloric acid, p- toluene sulphonic acid etc. afford 3-aryl-9-methyl-1,2,4-triazolo[4,3-a]qui nolines 3a-h by intramolecular oxidative cyclization in high yield. The pro bable mechanism for this transformation is also proposed.