Synthesis of an intermediate for A-ring of 19-nor-1 alpha,25-dihydroxyvitamin D-3 analogues

Citation
Y. Wu et al., Synthesis of an intermediate for A-ring of 19-nor-1 alpha,25-dihydroxyvitamin D-3 analogues, I J CHEM B, 40(2), 2001, pp. 136-138
Citations number
6
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
ISSN journal
03764699 → ACNP
Volume
40
Issue
2
Year of publication
2001
Pages
136 - 138
Database
ISI
SICI code
0376-4699(200102)40:2<136:SOAIFA>2.0.ZU;2-N
Abstract
An optically active intermediate 5b for the A-ring of 19-nor-1 alpha ,25-di hydroxyvitamin D-3 analogues has been synthesized in 9 steps, starting from readily available, inexpensive D(+)-xylose with good yield and cheap reage nts.