Extensive subcutaneous metastases from squamous cell carcinoma of the cervix in patient with HIV

Advanced human immunodeficiency viral disease is associated with a high pre valence of cervical squamous intraepithelial and invasive lesions and proba bly with a rapidly progressive course of disease. Metastases to the skin oc cur rarely in cervical cancer, even in terminal stage of the disease. A pat ient with human immunodeficiency virus (HIV) for 14 years was diagnosed wit h squamous cell cancer of the cervix, Stage I-B2 in June 1997. She underwen t successful radiotherapy. She then presented in January 1999 with recurren ce evidenced by extensive subcutaneous nodules and multiple metastases, The patient developed rapidly progressive disease and died within two months. Patients with HIV and cervical cancer may present with a more aggressive co urse of disease. Aggressive treatment and closer follow-up may be indicated .