Hm. Ko et al., Androgen receptor gene mutation associated with complete androgen insensitivity syndrome and Sertoli cell adenoma, INT J GYN P, 20(2), 2001, pp. 196-199
We report a case of Sertoli cell adenoma in complete androgen insensitivity
syndrome (CAIS) in a 22-year-old woman. Polymerase chain reaction-single s
trand conformation polymorphism and DNA sequencing revealed a single nucleo
tide substitution on exon 7 of the human androgen receptor (hAR) gene, resu
lting in a change of CGA (arginine) to CAA (glutamine) in codon 831.