The extent of lymph node dissection in stomach adenocarcinoma is currently
under debate. Japanese data strongly support the therapeutic value of exten
ded lymphadenectomy (D2 node dissection), whereas in Western countries seve
ral prospective trials have recently been completed with contrasting result
s. During the period May 1993 to May 1998, 164 patients with gastric cancer
were observed: 136 patients, treated with a radical surgical procedure inc
luding lymph node dissection according to the guidelines of the Japanese Re
search Society for Gastric Cancer, were eligible for our analysis. Clinical
, histopathological, and surgical factors were examined for their influence
on long-term survival. Our results on morbidity and mortality rates are si
milar to Japanese series: we suggest that the experience and training of th
e surgeon and his personal attitude towards extensive lymph node dissection
may, therefore, be a major factor influencing the morbidity associated wit
h the procedure. The relatively high estimated 3-year survival rate (52%) s
uggests support for extended lymphadenectomy (D2 dissection) in gastric can
cer as standard treatment.