COMPARISON OF EVANESCENT-WAVE SPECTROSCOPY BASED ON SILVER-HALIDE FIBERS WITH CONVENTIONAL ATR-IR SPECTROSCOPY

With improved optical and mechanical properties of crystalline silver halide fibres, the development of novel accessories, in particular of Bow-through cells with an inner volume of a few microlitres or disposa ble sensor parts for sample measurement, is possible. These features e nable process monitoring, for example, when only minute sample volumes at low flow rates are available such as in the case of in vivo blood glucose sensing using microdialysis. The performance of some fibre-opt ic sensors based on evanescent field absorption is compared with that of conventional attenuated total reflection spectroscopy equipment for studying microsamples of biofluids. (C) 1997 Elsevier Science B.V.