Peliosis hepatis is a rare benign condition that is histologically characte
rized by multiple cystic blood-filled spaces in the liver. Although the cau
se is unknown, the condition occurs in association with several diseases or
medications. We report a patient who was found to have a lesion with lipio
dol accumulation in the liver 2 months after its intraarterial injection. T
he lesion was diagnosed and treated as a small hepatocellular carcinoma. Ho
wever, subsequent right hepatic lobectomy and histologic examination confir
med the diagnosis of focal peliosis hepatis.