Background: There are both anecdotal clinical and laboratory experimental d
ata suggesting that low pH mouthrinses cause dental erosion. This evidence
is particularly relevant to acidified sodium chlorite (ASC) formulations si
nce they have plaque inhibitory properties comparable to chlorhexidine but
without the well known local side effects.
Aim: Studies in situ and in vitro were planned to measure enamel erosion by
low pH mouthrinses. The study in situ measured enamel erosion by ASC, esse
ntial oil and hexetidine mouthrinses over 15-day study periods. The study w
as a 5 treatment, single blind cross over design involving 15 healthy subje
cts using orange juice, as a drink, and water, as a rinse, as positive and
negative controls respectively 2 enamel specimens from unerupted human thir
d molar teeth were placed in the palatal area of upper removable acrylic ap
pliances which were worn from 9 a.m. to 5 p.m., Monday to Friday for 3 week
s. Rinses were used 2 x daily and 250 ml volumes of orange juice were imbib
ed 4 x daily. Enamel loss was determined by profilometry on days 5, 10 and
15. The study in vitro involved immersing specimens in the 4 test solutions
together with a reduced acid ASC formulation for a period of 4 h under con
stant stirring; Enamel loss was measured by profilometry every hour.
Results: Enamel loss was in situ progressive over time with the 3 rinses an
d orange juice but negligible with water. ASC produced similar erosion to o
range juice and significantly more than the two proprietary rinses and wate
r. The essential oil and hexetidine rinses produced similar erosion and sig
nificantly more than water. Enamel loss in vitro was progressive over time,
and the order from low to high erosion was reduced acid ASC. ASC, Essentia
l oil, and hexetidine mouthrinses and orange juice.
Conclusion: Based on the study in situ, it is recommended that low pH mouth
rinses should not be considered for long term or continuous use and never a
s pre brushing rinses. In view of the plaque inhibitory efficacy of ASC, sh
ort- to medium-term applications similar to those of chlorhexidine would be
envisaged.