We conducted a prospective randomized controlled double-blind trial at a re
gional referral centre for the Eastern Cape area, (Livingstone Hospital) to
determine whether the use of plastic adhesive drapes intraoperatively woul
d prevent Post Caesarean Section Wound Infection. A total of 620 patients u
ndergoing Caesarean section (CS) were enrolled for randomization in the tri
al. Fifteen patients were excluded, while 305 received drapes (test group)
and 300 did not (control group). Two patients in the control group were sub
sequently excluded.
The primary outcome measure was the presence of Post Caesarean Wound Infect
ion. A secondary outcome measure was the number of days in hospital post op
eration. The study and control groups were comparable at entry: Results sho
w that 34 patients in the test group (N=305) developed wound sepsis (11.1%,
) compared with 30 in the control group (N=298) (10.1%) (difference not sig
nificant; Fisher's exact test 0.6933). Average days spent in hospital posto
peratively were similar for both test (infected cases: mean 10.56 so 3.84;
non-infected cases: mean 5.21 so 1.3) and control groups (infected cases: m
ean 10.18 so 3.81; non-infected cases: mean 5.2 so 0.93) (NS). We concluded
that the use of plastic adhesive skin drapes did not avert PCWS or decreas
e the length of post operative stay in hospital for septic cases. (C) 2001
The Hospital Infection Society.