Three new phenolic compounds from a manipulated plant cell culture, Mirabilis jalapa

Bioassay-guided fractionation of an organic extract of the cell mass from a manipulated plant cell culture of Mirabilis jalapa led to the isolation an d subsequent identification of three new phenolic compounds, 1, 2, and 3. T he isoflavone 1 and dehydrorotenoid 2 were identified as the principal anti fungal principles from this plant cell culture with IC50's of 25 and 48 mug /mL, respectively, against the test organism, Candida albicans DSY1024. The rotenoid 3 was inactive at 200 mug/mL in this assay.