Synthesis of (+)-cyclozonarone and the absolute configuration of naturallyoccurring (-)-cyclozonarone

Authors
Cortes, M Valderrama, JA Cuellar, M Armstrong, V Preite, M
Citation
M. Cortes et al., Synthesis of (+)-cyclozonarone and the absolute configuration of naturallyoccurring (-)-cyclozonarone, J NAT PROD, 64(3), 2001, pp. 348-349
Citations number
9
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
64
Issue
3
Year of publication
2001
Pages
348 - 349
Database
ISI
SICI code
0163-3864(200103)64:3<348:SO(ATA>2.0.ZU;2-H
Abstract
Synthesis of(+)-cyclozonarone (1) has been achieved using (-)-polygodial(3) as chiral starting material. The absolute configuration of naturally occur ring (-)-cyclozonarone was established as 5R,10R by comparison of spectral data and optical rotation with those of (+)-cyclozonarone.