Participation in research: Informed consent, motivation and influence

Objective: To investigate the process and quality of informed consent, moti vation and influence in parents who were invited to enrol their baby in a r esearch project. Methodology: A mixed quantitative/qualitative questionnaire was sent to a c ohort invited to participate in a physiological research project on sudden infant death syndrome (SIDS) at the Dunedin Public Hospital, Dunedin, New Z ealand. Separate questionnaires were used for parents who participated (94) and those who declined to participate (103). Response rates were 69% and 4 7%, respectively. Results: All consenting parents felt they understood the purpose and proced ure of the study. The majority (90%) thought the information about the stud y was very good; 6.5% felt more detail was required. Eighty-five per cent f ound the verbal explanation the most useful source of information. All part icipated for altruistic reasons such as to aid SIDS research. Although 27% had concerns about safety of the tests, after the tests all responders felt happy with the safety of the tests. Inconvenience was the main reason (53% ) for declining to participate. Twenty-eight per cent of declining parents were concerned about the safety of the tests. Conclusion: Of those who responded to the questionnaire, the process for ob taining informed consent in the SLDS studies was satisfactory. Parents' mot ives for participating were mostly altruistic. The role of recall bias and selection bias may make the implications of this study unclear.