Enantioselective synthesis of hydroxy ketones through cleavage and formation of acyloin linkage. Enzymatic kinetic resolution via C-C bond cleavage

Authors
Demir, AS Pohl, M Janzen, E Muller, M
Citation
As. Demir et al., Enantioselective synthesis of hydroxy ketones through cleavage and formation of acyloin linkage. Enzymatic kinetic resolution via C-C bond cleavage, J CHEM S P1, (7), 2001, pp. 633-635
Citations number
33
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
14727781 → ACNP
Issue
7
Year of publication
2001
Pages
633 - 635
Database
ISI
SICI code
1472-7781(2001):7<633:ESOHKT>2.0.ZU;2-9
Abstract
Both enantiomers of benzoins and (R)-2-hydroxy-1-phenylpropanone analogues were obtained in high yield on a preparative scale starting from aromatic a ldehydes, rac-benzoins and aliphatic aldehydes via enzyme-catalysed C-C bon d cleavage and C-C bond formation reactions.