The efficient, enantioselective synthesis of quinoxaline, pyrazine and 1,2,4-triazine substituted alpha-amino acids from vicinal tricarbonyls

Authors
Adlington, RM Baldwin, JE Catterick, D Pritchard, GJ
Citation
Rm. Adlington et al., The efficient, enantioselective synthesis of quinoxaline, pyrazine and 1,2,4-triazine substituted alpha-amino acids from vicinal tricarbonyls, J CHEM S P1, (7), 2001, pp. 668-679
Citations number
42
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
14727781 → ACNP
Issue
7
Year of publication
2001
Pages
668 - 679
Database
ISI
SICI code
1472-7781(2001):7<668:TEESOQ>2.0.ZU;2-4
Abstract
The reaction of diamines and amidrazones with alpha -amino acid vicinal tri carbonyls has been shown to be a versatile route towards novel heterocyclic alpha -amino acids. This route is also applicable to parallel synthesis an d has allowed the formation of a range of heterocyclic amino acid systems.