We evaluated the usefulness of contrast-enhanced, wide-band harmonic gray s
cale imaging for the diagnosis of hepatocellular carcinoma and compared it
with helical computed tomography Forty-eight patients with 61 hepatocellula
r carcinoma lesions were scanned by contrast-enhanced, wide-band harmonic g
ray scale imaging after an intravenous bolus injection of the contrast agen
t Levovist. fifty-seven of the 61 hepatocellular carcinoma lesions showed h
ypervascular enhancement, and intratumoral vessels could be observed in 40
of the 57 lesions. Helical computed tomography revealed a high-attenuation
area in 54 of the 61 lesions, whereas the other lesions showed an equivocal
-attenuation area. Contrast-enhanced, wide-band harmonic gray scale imaging
is a useful method for diagnosing the vascularity of hepatocellular carcin
oma.