R. Frajndlich et al., Color Doppler sonographic study of the uterine artery in patients using intrauterine contraceptive devices, J ULTR MED, 19(8), 2000, pp. 577-579
A transvaginal Doppler sonographic examination of uterine artery blood flow
was performed. Resistance and pulsatility indices were measured in 101 wom
en, 74 of whom were using an intrauterine contraceptive device, and 27 cont
rols, who were not using any contraceptive method. The intrauterine contrac
eptive device users were divided into three groups: those with normal bleed
ing (n = 34); those with abnormal uterine bleeding without medication (n =
16); and those with abnormal bleeding corrected with use of prostaglandin i
nhibitors (n = 24). The resistance and pulsatility values were significantl
y lower in the group of women using intrauterine contraceptive devices who
had abnormal bleeding than in all other groups (P < 0.001). All other compa
risons were nonsignificant. A pulsatility index of less than 2 may be assoc
iated with a higher risk for development of intrauterine contraceptive devi
ce-induced bleeding.