The aim of this study was to identify sonographic predictors of patient out
comes or need for surgical intervention df acute thoracic empyema. All pati
ents with a clinical diagnosis of thoracic empyema underwent transthoracic
ultrasonographic examination and thoracentesis at admission. According to t
he presence or absence of septa in sonographic images, the patients were cl
assified into two groups: septated and nonseptated. Sonographic findings we
re analyzed with respect to duration of hospital stay, chest tube drainage,
and treatment efficacy. A total of 163 consecutive the study (83 patients
with patients were included in septated and 80 with nonseptated sonographic
images). The mean duration of hospital stay (35.4 versus 27.0 days, P = 0.
009) and chest tube drainage (13.1 versus 7.6 days, P < 0.001) for the pati
ents with septa were significantly longer than for those without septa. The
patients with septa were more likely to undergo intrapleural fibrinolytic
therapy (63.8% versus 38.8%, odds ratio 2.79, P = 0.001) and surgical inter
vention (24.3% versus 7.5%, odds ratio 3.92, P = 0.004). We concluded that
sonographic septation is a useful sign to predict the need for subsequent i
ntrapleural fibrinolytic therapy and surgical intervention in cases of acut
e thoracic empyema. Early fibrinolytic therapy or even surgical interventio
n may be indicated in patients with sonographic septations.