Our objective was to evaluate the preoperative clinical, laboratory, and so
nographic characteristics of struma ovarii in comparison to ovarian dermoid
cysts. A retrospective review of gynecologic patients operated on for matu
re cystic teratoma over a 10 year period identified 12 cases of struma ovar
y. These cases, combined with 4 additional cases from an earlier report, we
re the subject of this study. Results were compared to 32 cases of ovarian
dermoid cysts. Ovarian struma ovarii occurred in 12 (4.8%) of 251 cases of
ovarian dermoid cysts. Most patients were premenopausal, and the mean lesio
n diameter was 57.3 mm (range, 30-95 mm). Struma ovarii occurred more frequ
ently (68.8%) in the right adnexa and was seen with a normal CA-125 level.
Blood flow, assessed by Doppler ultrasonography, was located in the center
of the lesion in all cases of struma ovarii. Rare cases were seen with elev
ated tumor markers and low resistance blood flow With regard to dermoid cys
ts, blood flow had a higher resistive index. In addition, no blood flow cou
ld be detected from the center of the echoic lesion in dermoid cysts (P < 0
.0001). In summary, it is difficult to distinguish between struma ovarii an
d dermoid cysts on the basis of their sonographic appearance. Nevertheless,
Doppler flow may aid in the preoperative diagnosis of struma ovarii. Blood
flow signals, detected from the center of the echoic lesion, and low resis
tance to flow may be more common in struma ovarii.