T. Fujisawa et al., Influence of butyric and lactic acids on the beta-glucuronidase activity of Clostridium perfringens, LETT APPL M, 32(3), 2001, pp. 123-125
The beta -glucuronidase activity of intact cells of Clostridium perfringens
was not influenced by the presence of either 0.09 or 0.19% lactic or butyr
ic acids. In contrast, the enhanced enzyme activity of intact cells due to
sodium deoxycholate was significantly decreased by the presence of these ac
ids. These results suggest the possibility that the development of cancer d
ue to the intake of a high fat diet may be inhibited by the presence of org
anic acids produced by intestinal bacteria.