QUANTITATIVE CHROMATOGRAPHIC DETERMINATION OF MOENOMYCIN ANTIBIOTICS

A highly efficient system has been developed for separation of a mixtu re of moenomycin antibiotics (moenomycin A, B, and C extracted from fe rmentation broth) on silica gel HPTLC plates. The separation was achie ved in 45 min; the development distance was 70 mm. Quantitative analys is was achieved by scanning densitometry. It was established that coef ficients of variation did not exceed 5%.(sic) was used as the referenc e method. Good correlation was obtained between the results obtained u sing both techniques (r = 0.9873).